In the field of injections, brands such as Juvéderm and Restylane have become synonymous with hyaluronic acid fillers. It is well known that these fillers can smooth, plump and reshape areas of insufficient volume. Now, a new filler series named RHA 2, RHA 3 and RHA 4 from Revance Theraputics has entered the doctor’s office in the United States. Although their debut here makes us feel strange, they have been on the market in Europe for more than five years. .
To understand how these fillers compare to products already on the market, we talked with Ava Shamban, MD, a dermatologist in Beverly Hills, California, who also served as an investigator for RHA 2, 3, and 4 clinical trials.
NewBeauty: Which RHA filler is best for different parts of the face? Dr. Shamban: The main difference between each filler is the amount of cross-linking between them. RHA 2 is best for perioral lines and plumped lips. It can also be used for radial cheek lines and higher levels of dermis to obtain a smoother surface. RHA 3 can be used for nasolabial folds and commissures, or the corners of the mouth. RHA 4 is best for deeper nasolabial folds and deeper lines of the lower face and chin. It is also used outside the label in the middle of the face to outline the contours of the cheeks.
Note: When describing the performance of these fillers, the word “sports” appears. How does exercise work when injecting dynamic areas of the face? Shamban: Yes, sports ingredients are the key to these fillers. The best improvement of the filling is that the face is as good when it is still as it is when it is in motion. These fillers blend well into the tissue, which means they will not be detectable and provide what I call “softer” results.
Since RHA is most similar to the natural hyaluronic acid present in our skin and is very suitable for our tissues, it has the greatest flexibility. Therefore, we are able to provide patients with excellent results from all angles throughout the movement of the patient’s most dynamic facial area.
Note: Can you explain what crosslinking is and the specific crosslinking method of RHA filler makes it unique? Shamban: The free hyaluronic acid present in skin care, as well as our natural hyaluronic acid, will be quickly decomposed and metabolized in about 48 hours. To prevent this from happening in dermal fillers, these HA chains are cross-linked with suspended chemical proteins. The fewer chemical proteins needed in the manufacturing process, the fewer modifications and additional processes, and the products produced are cleaner and ultimately cleaner.
The difference between RHA and the first generation of hyaluronic acid dermal fillers is that there are fewer chemical modifications and crosslinks in the longer HA chains. Therefore, RHA products are most similar to natural products in our body in terms of flexibility in use, natural effects and longevity. This is why they cannot be detected regardless of facial movement, as I often say-we only want to see the result, not the product.
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Post time: Nov-11-2021